Sibutramine Hydrochloride (Sibu Med) 20mg/tab 60 Tablets

Product Details

Active Ingredient: Sibutramine Hydrochloride

Amount of Active Ingredient: 20 mg/tab

Product Form: The package contains 60 tablets

Brand Name: Sibu Med

Manufacturer: Bioniche Pharma

• Sibutramine is a drug for the treatment of obesity.  
• The drug has an anorexic effect, suppressing hunger and increasing body temperature.  
• Sibutramine activates beta-adrenergic receptors and suppresses reuptake by brain neurotransmitters.  
• The medication may cause side effects, including increased blood pressure and heart rate.  
• Sibutramine does not cause a psychostimulating effect, but activates the "hormones of joy" - serotonin and dopamine.  
• The drug can be dangerous if used for a long time, causing addiction and increasing the risk of cardiovascular diseases.  
• Sibutramine can only be prescribed by a doctor after the necessary examinations have been performed.

Pharmacological action

Sibutramine is a medicine intended for the treatment of obesity, which has a central effect on the body. Its main property is the anorexic effect: it suppresses hunger and also increases body temperature, which promotes more active fat burning. As a result, the amount of food consumed decreases and the amount of body fat decreases.

The treatment of obesity with sibutramine has shown its effectiveness: the weight goes away quite quickly. However, like any antidepressant, this medicine has side effects.

The uniqueness of sibutramine lies in the fact that it does not cause a psychostimulating effect. Instead, it activates beta-adrenergic receptors and suppresses the reuptake of brain neurotransmitters, including serotonin and dopamine, the so—called "hormones of joy." Weight loss occurs due to a decrease in cholesterol and uric acid levels, as well as an increase in lipoprotein levels.

Some facts about the medicine:

• When using it, there is a slight increase in blood pressure and heart rate.
• The medicine is absorbed by 78% and reaches its maximum concentration in the blood 1.5-2 hours after ingestion.
• The medicine processing process mainly occurs in the liver, and traces of it in the blood are detected within 4 days.

Sibutramine: description, composition, effect and properties

Sibutramine is a fine powder of white or cream color. Its shade may vary depending on the impurities included in the composition and some physical parameters, such as humidity levels.

When taking the medicine, a person feels a sense of fullness, which makes it popular among those who seek to lose weight. The medicine is usually prescribed not as an independent medicine, but as part of a complex therapy.

At the beginning of its use, high hopes were pinned on this medicine, but its psychotropic properties were soon discovered. After long-term use of sibutramine was proven to be addictive, its use was banned in many countries. However, its production has not stopped. The medicine is rapidly absorbed into the blood and excreted by the kidneys.

Effectiveness

Numerous studies confirm that this medicine is really effective in the fight against excess weight. For example, in an experiment involving 605 obese people, after two years, people's weight dropped three times and their waistline became twice as thin as that of those who took a placebo. However, not everyone can maintain the achieved result, and in 20% of cases, excess weight returns after treatment.

Studies have also shown that sibutramine can be dangerous to human health if used regularly. The risk of developing cardiovascular diseases, such as heart attack and stroke, increases by more than 15%. Of the group of subjects, 1.5% of people with cardiovascular complications were rescued in intensive care. However, the percentage of people with heart and vascular diseases in the groups taking the medicine and placebo was the same.

The effect of the medicine on the human body

Sibutramine is a psychostimulant that reduces appetite and eliminates the subjective need for food. The following disorders are observed when using the medicine:

• slight increase in heart rate;
• slight increase in blood pressure;
• increased blood concentrations of low-density lipoproteins, total cholesterol, and uric acid.

The psychotropic effect of sibutramine is explained by its ability to inhibit the reuptake of neurotransmitters responsible for positive emotions. Simply put, the "hormones of happiness" are in a free state and bind to specific receptors, which leads to the activation of biochemical reactions that are clinically manifested in the form of comfortable sensations.

The medicine is prescribed for obesity caused by overeating, especially in cases where this leads to the development of diabetes, cholelithiasis and other pathologies. However, it should be remembered that sibutramine can also have a pathological effect, therefore, its use is contraindicated in the following cases:

• Obesity of a non-nutritional nature (for example, due to hormonal disorders);
• Refusal to eat during stressful situations;
• Mental disorders;
• Cardiovascular diseases;
• Disorders in the brain.

This medicine should not be taken by people with any form of dependence: on medicine, alcohol or medicine. It should also not be combined with some other medications, such as antipsychotics and antidepressants.

Sibutramine belongs to the group of medicine that have a calming and relaxing effect. If combined with alcohol, the patient may experience a strong sedative effect. Small doses of Sibutramine in combination with alcohol will not have a significant negative effect. However, regular alcohol consumption while taking the medicine can lead to anxiety, insomnia, and decreased physical activity.

Legality

Since 2008, Sibutramine and medicine based on it have been included in the list of potent substances subject to strict accounting. Some of them can be classified as doping. In many countries, it is impossible to buy medicine with sibutramine without a prescription.

Side effects

• thirst, dry mouth;
• headaches;
• dizziness;
• tachycardia;
• increased blood pressure.

Insomnia, hemorrhoids, and stool problems may be just the most minor of the side effects that may occur when taking sibutramine. However, in addition to these generally harmless ones, more serious complications may occur that require immediate discontinuation of the medicine.

The most common side effects that may occur as a result of taking sibutramine are:

• Hypertension
• Ischemia
• Bulimia
• Anorexia
• Mental disorders
• Disorders of the gastrointestinal tract
• Negative effect on potency
• Addiction and strong craving for capsules
• Depression, anxiety
• Fainting, loss of consciousness
• Anemia

Many people start taking the medicine on their own, without consulting a doctor. However, uncontrolled intake, without taking into account contraindications, can lead to serious health problems. Only a doctor, after conducting the necessary examinations, can prescribe a certain medicine to a patient in the right dosage and for a certain period of time.